The study compared the effectiveness of a combination of two vaccines with the usual two doses of Pfizer or AstraZeneca vaccines. Results: Both combinations, with Pfizer vaccine first and then AstraZeneca or vice versa, work well, helping to strengthen the immune system. Specifically: Prior administration of AstraZeneca vaccine and posterior Pfizer vaccination produced higher antibody and T-cell responses than prior Pfizer and AstraZeneca administration. Both vaccine combinations produced higher levels of antibodies than using 2 doses of AstraZeneca vaccine. The antibody response was highest with both doses of Pfizer vaccine, but the highest T-cell response was combined with the first dose of AstraZeneca vaccine and the second dose with Pfizer's vaccine.
This assertion gives flexibility to ongoing vaccination campaigns, experts say. Many countries have combined injections of two different vaccines. According to the BBC, Spain, Germany... for young people to switch to a second dose of Pfizer or Moderna's mRNA vaccine if they have had the first dose of AstraZeneca vaccine, after it was concluded that the vaccine was of AstraZeneca was associated with a very rare blood clotting complication several months ago.
Getting two full doses of the COVID-19 vaccine is important to provide maximum protection against COVID-19 disease and trains our bodies to make antibodies and T cells to prevent and destroy them. virus removal. Professor Matthew Snape, of the University of Oxford, who led the study, said that although the interval between the two injections in the study was 4 weeks instead of 12 weeks as is common practice in the UK, combining the two vaccines still gives found effective. The 12-week interval between the two injections was confirmed to in fact produce a better immune response. Also, according to the study, people who received two doses of the AstraZeneca vaccine may have a stronger immune response if they get a booster shot with another vaccine.
Due to an abundant supply of vaccines, the UK does not intend to change its strategy of injecting two doses with the same vaccine to the population. However, the country's authorities say the study provides the health sector with greater flexibility, especially when it comes to booster doses at a later time. In addition, in countries that are implementing vaccination, if there are difficulties in vaccine supply, they can flexibly switch to another vaccine without worry.
Reference as Tuoi Tre Online